Is Omega 3 effective for Meibomian Gland Dysfunction?
- July 5, 2018
Dry Eye Assessment and Management Study Research Group, Asbell PA, Maguire MG, Pistilli M, Ying GS, Szczotka-Flynn LB, Hardten DR, Lin MC, Shtein RM.
N Engl J Med. 2018 May 3;378(18):1681-1690.
DREAM study concluded that supplements containing 3000 mg of n-3 fatty acids （Omega 3）for 12 months did not have significantly better outcomes than those who were assigned to receive placebo.
This was a multicenter, double-blind clinical trial. 349 patients who took 3000ｍg omega 3 supplements,186 placebo-group for 12 months were evaluated tear-film parameters including OSDI, BUT, CFS, and the Schirmer value. As results, all scores didn’t show significantly differences between before and after the treatment. I
HOWEVER, all of the evaluated parameter were related to aqueous-deficient dry eye and short BUT-type dry eye, not meibomian gland dysfunction (MGD). Don’t worry about that.
I believe the efficacy of Omega 3 on MGD patients. There are several double-blind clinical trials which reported the efficacy of Omega 3 on MGD patients for 3 or 6 months.
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