About LIME

Project Leaders

Project Leaders

Shima Fukuoka Dr.

Shima Fukuoka

Omiya Hamada Eye Clinic

Mizoguchi Takanori Dr.

Takanori Mizoguchi

Mizoguchi Eye Clinic


Hirayama Osama Mohamed Aly Ibrahim

Department of Ophthalmology,Tokyo Dental College, Ichikawa General Hospital

Although meibomian gland dysfunction (MGD) is the most commonly associated dry eye disease in the elderly that affects the health and well-being of millions of people around the world, its incidence is conceivably underestimated.
I have been conducting research on MGD using animal models such as Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice, as well as imaging techniques including Confocal microscopy. I am very interested in understanding the fundamental biological processes behind MGD such as inflammation and its relation to reactive oxygen species (ROS). I believe that the better understanding and proper treatment of MGD will help in improving the quality of life for dry eye patients not only in Japan but also around the world.